Thousands of people have turned out to welcome the Paralympic flame which is en route to the Olympic Stadium for the opening ceremony of the Games later.
Crowds have lined the route of the 24-hour torch relay which began in Stoke Mandeville - the spiritual home of the Paralympics - on Tuesday night.
Four national flames were united in a ceremony at Stoke Mandeville Stadium.
The Queen and the Duke and Duchess of Cambridge are among those due to attend the opening ceremony.
Crowds gathered in the market square in Aylesbury, Buckinghamshire, to watch the start of the relay and thousands more turned out overnight to cheer on the torchbearers along the route.
Guard of honourRunning about two hours late, the flame, which is being carried by 580 torchbearers, is next due to arrive at Britain's first traditional Hindu temple, the Shri Swaminarayan Mandir Temple in Brent.
It will then visit Lord's Cricket Ground, London Zoo and the Abbey Road crossing made famous by the Beatles among other landmarks.
In Trafalgar Square later, former boxer Michael Watson, wheelchair racer Dame Tanni Grey Thompson and Paralympic swimmer Chris Holmes will carry the flame.
About 3,000 invited guests, including Paralympians, representatives from disability groups and local residents, attended Tuesday evening's ceremony at Stoke Mandeville Stadium.
Some 150 local residents took part in a lantern procession and formed a guard of honour for eight torchbearers who carried flames representing England, Scotland, Northern Ireland and Wales.
These flames were then used to creat the Paralympic flame in a ceremonial cauldron.
Speeches were made by International Paralympic Committee (IPC) president Sir Philip Craven, Lord Coe, chairman of Games organisers Locog, and Culture Secretary Jeremy Hunt.
Eva Loeffler, the daughter of the founder of the Paralympic Games, Dr Ludwig Guttman, also paid tribute to the role the Stoke Mandeville Games - and her father - had in defining the modern Paralympic movement.
Shortly after 20:00 BST on Tuesday, the first team of torchbearers - Paralympians chosen by the IPC - left the stadium, signalling the start of the 24-hour torch relay.
Just before midnight the torch was carried through the village of Weston Turville, in Buckinghamshire, where residents lit candles to line the route.
A London 2012 spokeswoman said: "It is great. Each place has got a different way of doing things.
"In Weston Turville the candles along the street were superb, in Tring it was the sheer number of people, and in Berkhamsted there was music while the torch went along the High Street, and when it left the church bells rang out."
When it arrives at the Olympic Park in Stratford, east London, it will be used to light the cauldron during the opening ceremony of the Games.
The event, called Enlightenment and created by Bradley Hemmings and Jenny Sealey, will showcase the skills of disabled artists with a cast of 3,000 adult volunteers including injured soldiers and past Paralympic athletes.
The four national flames were kindled at the summit of the highest peaks in Scotland, Northern Ireland, England and Wales last week.
They were used to light ceremonial cauldrons in London's Trafalgar Square on Friday, outside Stormont in Northern Ireland on Saturday, at the Mound in Edinburgh on Sunday and outside City Hall in Cardiff on Monday.
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